Jun 14, 2025

2025 Million Dollar Bike Ride

Riding for Rare Disease Research

$3,620Raised of $1m

Because no disease is too rare

The Million Dollar Bike Ride brings over 600 cyclists and volunteers to Penn’s campus to ride either 10, 32, or 70 miles starting in the city, and ranging across the Greater Philadelphia region. In 11 years, the MDBR’s 30+ teams have raised over $22 million to fund research grants on the diseases they represent.

One in ten Americans is living with a rare disease, and over 300 million individuals are affected worldwide. Register today for the Million Dollar Bike Ride to raise much needed awareness and funding for the rare disease community!

How It Works

🚲 Why should I participate?

The Million Dollar Bike Ride raises critical funds for rare disease research. By registering today, you can help your disease team meet their goal and support rare disease research!

🚲 How can I participate?

There are two easy ways to help!

Create a peer-to-peer fundraising page to raise money by clicking on the "Register" button at the top of this page.

Donate to one of the participants or teams found above.

🚲 What are the goals of the event?

To raise money and awareness for rare diseases!

Donations

Our Sponsors

A Note About 2025

Organizations participating in the 2025 Million Dollar Bike Ride will receive the funds raised by their team. Your donation plays a pivotal role, allowing organizations to not only support rare disease research, but make a direct impact on patients and families in their rare disease community. Thank you!

Million Dollar Bike Ride is coordinated by Penn Medicine's Orphan Disease Center. Funds from the 2025 Million Dollar Bike Ride are being distributed to teams through partnership with rare-disease nonprofit, Uplifting Athletes.